Patients with adverse ocular events due to Dupixent® treatment

Dupixent (dupilumab) injection is an interleukin-4 receptor alpha-antagonist indicated for the treatment of adult patients with moderate-to-severe atopic dermatitis (eczema) and whose symptoms are not adequately controlled with topical prescription therapies or when those therapies are not advisable. Dupixent can be used with or without topical corticosteroids.

As a doctor of optometry, you should be aware that there are potential common ocular side effects that users of the medication may experience. 

  • Conjunctivitis
  • Blepharitis
  • Keratitis
  • Eye pruritus
  • Herpes simplex virus infection
  • Dry eye

You are uniquely positioned to help patients who may experience these symptoms. The American Optometric Association encourages doctors of optometry to reach out to local dermatologists to establish your primary eye health care practice as the preferred referral for their patients experiencing any ocular side effects. Following is a template outreach letter for personalization to send to dermatologists in your community.  You can find more information about the treatment and side effects at And, should you have any questions or additional needs, please reach out to Michael Duenas, O.D., at MRDuenas@AOA.ORG.